Myc binding protein
Web9 apr. 2024 · 23077 - Gene ResultMYCBP2 MYC binding protein 2 [ (human)] This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, … Web25 nov. 2024 · The MYC oncogenes encode a set of 3 highly related proteins that feature prominently in cancer. Overexpression of at least one MYC protein is observed in more …
Myc binding protein
Did you know?
Web29 jun. 2024 · Omomyc proteins can form homodimers and outcompete MYC–MAX for DNA binding 123 or can heterodimerize with either MYC or MAX 122 to titrate either … WebIkBa Protein, activated, 10 µg Activated, full length, recombinant human IκBα. N-terminal c-Myc, 6His-tagged. Phosphorylated in vitro using IKKα, active. For use in Enzyme …
Web1 jul. 2008 · c-myc mRNA and protein are short lived (approximately 20–30 minutes, each) and rare . Usually, c-myc is expressed at low levels, as low as one transcript per cell. … WebComplex assembly. The TATA-box binding protein (TBP) is required for the initiation of transcription by RNA polymerases I, II and III, from promoters with or without a TATA box. In the presence of a TATA-less promoter, TBP binds with the help of TBP-associated factors (TAFs). TBP associates with a host of factors, including the general transcription factors …
WebTo assess the molecular function of MYC-binding protein, Furusawa et al. (2001) performed a 2-hybrid screening of cDNAs encoding AMY1-binding proteins, with AMY1 as a bait using a human HeLa cDNA library. They found a clone encoding AKAP149 (AKAP1; 602449).AMY1 was found to bind in vitro and in vivo to the regulatory subunit II-binding … Web1 nov. 1998 · The cloning and further characterization of the mouse CRD-BP, a 577 amino acid protein containing four hnRNP K-homology domains, two RNP domains, an RGG …
WebMYC PROMOTER-BINDING PROTEIN Alternative titles; symbols IRLB HGNC Approved Gene Symbol: DENND4A Cytogenetic location: 15q22.31 Genomic coordinates (GRCh38): 15:65,659,123-65,792,293 (from NCBI) TEXT Cloning and Expression Stasiv et al. (1994) reported the cloning of a cDNA encoding a c-myc promoter-binding protein called IRLB.
WebThe KD value for 2xMyc-MBP is about 1,000 fold smaller, indicating a considerable increase of affinity and binding strength and demonstrating the outstanding IP performance of … baki dalam englishWebN-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene. ... MYCN binding to C-terminal domains of tetrameric p53 impacts p53 promoter selectivity and interferes other cofactors binding to this region. See also. Myc; References Further ... baki dalam bahasa inggerisWebMYC binding to MIZ1 is also crucial to inhibit p21CIP1 transcription. It is well known that p21CIP1 plays an important role in cell growth and differentiation, and that MYC inhibits cellular differentiation. MYC binds to p21CIP1 core promoter through interaction with the DNA-binding protein MIZ1. ar campers yassWebA basic helix–loop–helix (bHLH) is a protein structural motif that characterizes one of the largest families of dimerizing transcription factors. The word "basic" does not refer to complexity but to the chemistry of the motif because transcription factors in general contain basic amino acid residues in order to facilitate DNA binding.. bHLH transcription factors … arcam rlink manualWeb29 sep. 2024 · MYC, as a well-known oncogene, plays essential roles in promoting tumor occurrence, development, invasion and metastasis in many kinds of solid tumors and … bakidan lenkerana nece km dirWeb29 mrt. 2024 · At the minor promoter, DNase I footprints at a consensus c-Myc binding site and three Sp1 binding sites showed little variation during the G 1-to-S phase transition. … arcam p38 ebayWeb1 nov. 1998 · Abstract. The half-life of c-myc mRNA is regulated when cells change their growth rates or differentiate.Two regions within c-myc mRNA determine its short half … arcam rblink manual