WebApr 22, 2024 · Expressions of BTG3 mRNA and miR-93 are negatively correlated in ESC cells and tumor samples. a, b Expressions of BTG3 mRNA (a) and miR-93 (b) were examined in human esophageal squamous epithelial cell line HET-1A and ESC cell lines OE-19 and OE-33.c, d Expressions of BTG3 mRNA (c) and miR-93 (d) were examined … WebMar 29, 2024 · CDKN1B. cyclin dependent kinase inhibitor 1B. Gene ID: 1027, updated on 6-Nov-2024. Gene type: protein coding. Also known as: KIP1; MEN4; CDKN4; MEN1B; …
CDKN1A and CDKN1B Polymorphisms and Risk of Advanced …
WebMar 10, 2015 · Patient peripheral blood cells showed a significant 3-fold decrease in CDKN1B mRNA levels compared to controls, consistent with haploinsufficiency. The patient was 1 of 15 Spanish individuals with MEN-like features who underwent direct sequencing of the CDKN1B gene and was the only patient found to carry a mutation. WebDec 3, 2024 · Here we report that GTPase-activating protein SH3 domain–binding protein 1 (G3BP1) is critical for DNA sensing and efficient activation of cGAS. G3BP1 enhanced … gentry county mo historical society
Understanding Your Positive CDKN1B Genetic Test Result
WebThe CDKN1B gene, encoding for the CDK inhibitor p27 kip1 , is mutated in defined human cancer subtypes, including breast, prostate carcinomas and small intestine neuroendocrine tumors. WebFeb 17, 2024 · BTG3 overexpression up- regulated the protein expression of Cyclin E, p16, p27, NF-κB, p38α/β, XIAP, Bcl-2, ATG14 and p53, but down-regulated the mRNA expression of MRP1, BCRP, and mTOR in ... WebMar 20, 2024 · Here we show that genetic deletion of Cdkn1b in ACI rats susceptible to estrogen-induced mammary tumors decreases the relative fraction of Cd49b+ luminal progenitors identifying p27 as a key regulator of the proliferation and pool size of these cells. Progesterone, acting via the progesterone receptor (Pr), is an important regulator of … chris gollon artist